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                FaceSay™ Paper Published in Journal of Autism and Developmental Disorders 02/06/2011
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                The paper on the 2007 Randomized Controlled Study of FaceSay has successfully completed the peer review process at the Journal of Autism and Developmental Disorders (see the online version).  Here's a quick excerpt from the abstract

                "The children with LFA demonstrated improvements in two areas of the intervention: emotion recognition and social interactions. The children with HFA demonstrated improvements in all three areas: facial recognition, emotion recognition, and social interactions. These findings, particularly the measured improvements to social interactions in a natural environment, are encouraging"
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                Summary of Encouraging Research Results 10/06/2010
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                Four Randomized, Controlled Studies of FaceSay™ have been completed since 2007.  The FaceSay participants, when compared to the control participants, demonstrated statistically significantly improvements in an impressive range of measures:

                Playground Interactions With Peers (an unmatched breakthrough)
                Standardized Emotion Recognition Tests (Ekman, NEPSY II)
                Standardized Face Recognition Tests (Benton)
                Theory of Mind Tests (NEPSY II)
                Parent Self Reports (SSRS)

                While still far from FDA-grade evidence, these results are unmatched by any Social Skills technology intervention for students with an Autism Spectrum Disorder.

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                Randomized Controlled Study of FaceSay™ in California Elementary Schools 10/06/2010
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                As part of her dissertation, Linda Rice, a School Psychologist for a California School District, conducted what is now the fourth Randomized, Placebo Controlled Study of my FaceSay Social Skills Software.   The study included 32 high functioning students with an ASD (Kindergarten-5th). Half of the students were randomized to a lower dose FaceSay™ intervention, and the other half to the students' usual weekly computer lab activity, SuccessMaker®. The participants played these games in the computer lab for 25 minute sessions, once a week for 10 weeks.  No touch screens were used.  The children did not receive any social skills training in school.  In prior studies, the FaceSay dosing was twice per week and included touch screens and participants were in private schools with special support for autistic students.

                Given the lower dose, and the more challenging environment, the outcomes were surprisingly good.  The blinded playground observations, which were a breakthrough in Dr. Hopkins' study, were not significant, as I expected.  The blinded Teacher reports (SRS) approached, but were not significant, similar to Dr. Hopkins' study (parent SSRS).  As expected, the Emotion Recognition (NEPSY II Affect Recognition subscale) was statistically significant (p < .001).

                The big surprise for me was that the Theory of Mind measure (NEPSY II ToM subscale) was significant (p < .001).  This is something we had not measured before and which was very encouraging, particularly given the combined lower dose and more challenging school environment.
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                Dr. Hopkins\\\' RCT (N=49) submitted to Peer Reviewed Journal 10/19/2009
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                Dr. Maria Hopkins submitted a paper on her 2007 randomized controlled trial of FaceSay to a peer reviewed journal.  It is actively under review ("noteworthy contribution" commented one reviewer). 

                The paper is now online (Feb 2011)
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                MultiBaseline Study of FaceSay w/ 7 low functioning school aged children with autism 03/05/2009
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                AN APPLICATION OF COMPUTER-BASED TRAINING ON EMOTION DISCRIMINATION IN CHILDREN WITH AUTISM: A COMPARISON TO NON-COMPUTER-BASED TRAINING
                by Amy Schrembs


                Abstract: 
                The efficacy of the computer software program FaceSay™ in helping to teach discrimination between emotions correlated with facial expressions was evaluated in comparison to non-computer-based training on a multiple baseline schedule in low functioning children ages 7-11 (n=7), diagnosed with autism. The participants were assessed on their ability to correctly match emotion labels to pictures of emotional affect using the Ekman and Friesen (1976) series of photographs. The data indicate a general improvement in the participants ability to discriminate emotional states based on facial expression, although in some participants the level of improvement was greater than others. The data also generally shows a greater improvement in the abilities of participants who completed more sessions of the computer-based instruction. Conclusiveness of the computer program’s exclusive effects on recognition of emotion in facial expression however is challenged by observed increases in recognition abilities following baseline sessions of instruction in some participants. Overall, the results suggests that protracted exposure to the Facesay™ program will likely produce an increase in the ability of children with autism to discriminate facial expressions.

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                Scientific Advisors 01/15/2009
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                Dr. Matthew Goodwin, the Director of Clinical Research at the MIT Media Lab, and Associate Director of Research at the Groden Center, has kindly agreed to be a scientific advisor for studies of FaceSay.

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                RCT of FaceSay's Gazing and Face Recognition games, w/ 60+ 4yo Neurotypical Head Start Students 05/06/2008
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                Trista Perez, a grad student at UAB, successfully defended her master's thesis, "Social Skills Training in a Head Start Population" this month.  The was a randomized controlled trial with 60+ neurotypical preschool children.  The group that played FaceSay's "Bandaid Clinic" game showed statistically significant improvements in the Benton Face Recognition test.   o

                "Children’s ability to recognize faces varied significantly based on group assignment nF(2,73) = 7.62, p < .001, with an effect size of 0.17. (Power=0.98) nChildren playing FaceSay™ showed higher scores in a test of face recognition following the 12 week intervention"

                Just as interesting is what was not seen.   In this HeadStart study, only two of the FaceSay games, "Amazing Gazing" and "Bandaid Clinic" were used.  The old version of the "Follow the Face" game, at the time, was thought to be too difficult for the kids and was omitted.  "Follow the Face" is the FaceSay game that teaches not emotions explicitly, but an awareness of the physical antecedents of emotions, the facial movements.  Interestingly, none of the children in this study showed the improvement shown by the higher functioning autistic children in the first study on the Emotion Recognition test.  The difference is that the children in the first study played all three FaceSay games, including the "Follow the Face" game.

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                Encouraging Social Development in Children w/ Autism 06/19/2007
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                Demonstration and Evaluation of Avatar Assistant:
                Encouraging Social Development in Children with Autism Spectrum Disorders

                Maria Hopkins, PhD
                Fred Biasini, PhD
                The University of Alabama at Birmingham


                The overall purpose of our third study was to determine if a computer-based social skills intervention for children with autism or Asperger Syndrome is effective in improving specific social skills.

                View the PowerPoint presentation given at UA Tuscaloosa

                Specific Aims:
                - The study investigated the effects of an avatar assistant on children with ASD’s emotional cognition.
                - The study examined the social skills effects of the intervention.

                Measures:

                - Social Skills Rating System
                - Social Skills Observation
                - Emotional Cognition
                - Kaufman Brief Intelligence Test (KBIT)
                - Childhood Autism Rating Scale
                - Benton Test of Facial Recognition

                Participants:
                - Children with autism (n=25) or Asperger Syndrome (n=24)
                - Diagnosis based on DSM-IV criteria
                - Age range 6-15 (M = 10.17)
                - 44 boys; 5 girls
                - Mitchell’s Place, Glenwood, Shelby County schools

                Intervention and Control:
                - FaceSay and Tux Paint
                - 12 sessions (2 per week for 30 minutes)
                - One child per computer
                - 1-2 research assistants
                - Touch screens
                - Attendance rates >83% (10 sessions)
                - Rewards

                Participant Demographics:
                Group:             Autism                       Aspergers
                Variable:   Training   Control      Training   Control
                Age            10.31      10.57           10.05        9.85
                                 (3.31)      (3.20)          (2.30)      (2.87)
                IQ              55.09       54.79           91.88      93.04
                                (20.91)    (16.41)         (19.54)    (25.47)
                CARS          36.64       36.92           34.01      35.03
                                 (3.93)       (5.79)          (5.26)     (5.22)

                Results 1:  Emotion Recognition

                Group:             Autism                       Aspergers
                Measure     Control   Training      Control   Training
                Adjusted       5.23       6.53             6.79        8.7
                Means of       (p < 0.05)                    (p < 0.05)
                Emotion

                Recognition
                Autism:    Total emotional skills, F(1, 21) = 6.40,  p < 0.05
                Asperger: Total emotional skills,
                F(1, 20) = 23.04,  p < 0.001

                Post hoc analysis: 

                R2 = 0.873, F(3, 21) = 55.96, p < 0.001
                Higher KBIT scores and pre-test Emotion Composite scores were related to higher post-test Emotion Composite scores.

                Results 2:  Facial Recognition
                Group:             Autism                       Aspergers
                Measure     Control   Training      Control   Training
                Adjusted    12.84        14.48         15.42      18.41
                Means of       (p > 0.05)                    (p < 0.05)
                Facial
                Recognition

                Autism:     Benton-Short form F(1, 21) = 0.69, p > 0.05
                Asperger:  Benton-Short form F(1, 20) = 8.29, p
                < 0.01

                Results 3:  Parent Reported Social Skills
                Group:             Autism                       Aspergers
                Measure     Control   Training      Control   Training
                Adjusted    58.51        64.99         62.27       67.77
                Means of       (p < 0.05)                    (p = 0.05)
                Social
                Skills
                Rating
                Autism:     SSRS, F(1, 21) = 10.36,  p < 0.05
                Asperger:  SSRS, F(1, 20) = 4.36,  p
                = 0.05

                Results 4:  Observed Social Skills

                Group:             Autism                       Aspergers
                Measure     Control   Training      Control   Training
                Adjusted      11.04        9.6           10.46      7.54
                Means of      (p < 0.05)                    (p < 0.05)

                Social
                Skills
                Observation

                Autism:    F(1, 21) = 5.05,  p < 0.05
                Asperger: F(1, 20) = 13.61, p < 0.001

                Post hoc analysis: 
                R2 = 0.209, F(3, 21) = 3.12, p < 0.05
                Higher CARS scores (e.g. more autism symptoms) were related to higher post-test Social Skills Observation scores (e.g. more inappropriate social interactions)

                Acknolwedgements
                Autism Lab
                Symbionica
                Dr. Franklin R. Amthor
                Civitan International
                Mitchells' Place
                Glenwood

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